Medical titanium material It is a widely used material in the medical field. Its excellent biocompatibility and mechanical properties make it an ideal choice for medical devices and orthopedic implant materials. However, medical titanium materials have a certain degree of hydrophilicity and are easy to form oxide layer, which has certain restrictions on cell adhesion and tissue growth. In order to improve these problems, it is often necessary to apply some special treatment on the surface of medical titanium materials to improve their biocompatibility and histocompatibility.

At present, the surface treatment of medical titanium materials is mainly divided into physical treatment and chemical treatment. Physical treatment mainly changes the surface morphology, roughness and structure of medical titanium materials to increase their surface area and surface activity, thus improving their biocompatibility. Common physical treatment methods include mechanical grinding, sand blasting, electrochemical polishing, anodic oxidation, etc. Chemical treatment is mainly to form a layer of chemical reaction products on the surface of medical titanium materials, such as oxides, nitrates or calcium phosphorus compounds, to change their surface properties and enhance their interaction with cells and tissues. Common chemical treatment methods include pickling, acid-base treatment, chemical deposition, etc.

The surface treatment of medical titanium material has an important influence on its application effect. First, surface treatment can change the surface morphology and roughness of medical titanium materials, increase their surface area and surface activity, and thus increase their contact area and adhesion ability with tissue cells. The research shows that after proper surface treatment, the surface roughness of medical titanium materials can reach the similar level of biological tissues, which is conducive to cell adhesion and growth. In addition, by changing the surface morphology and structure of medical titanium materials, the adsorption and release behavior of its chemical substances on its surface can be regulated, thus realizing the regulation of cells and tissues.

Secondly, the surface treatment of medical titanium can also change its surface chemical properties, such as surface charge density, hydrophilicity and hydrophobicity. The research shows that, compared with ordinary titanium materials, medical titanium materials after proper surface treatment have more active groups and higher hydrophilicity, which is conducive to cell adhesion and diffusion. In addition, by changing the surface chemical properties of medical titanium materials, it can also regulate the reaction of cells and tissues to them, such as cell adhesion, proliferation and differentiation. For example, calcium phosphate treated medical titanium materials have good bone histocompatibility and bioactivity, which can promote the adhesion of bone cells and the growth of bone tissue.

Third, the surface treatment of medical titanium materials can also change its surface energy and surface tension, thus affecting the adhesion and growth behavior of cells and tissues. The research shows that after proper surface treatment, the surface energy and surface tension of medical titanium materials can be regulated, thus affecting their interactions with cells and tissues. For example, some studies have found that medical titanium materials with certain treatment have lower surface energy and surface tension, which can enhance cell adhesion and growth. This is because low surface energy can reduce the affinity between medical titanium materials and cells, reduce the rejection of cells, and thus facilitate cell adhesion and growth.

At the same time, the surface treatment of medical titanium materials can also change its surface microstructure and mesoscopic structure, thus affecting its mechanical properties and biocompatibility. The research shows that after proper surface treatment, the microstructure and mesoscopic structure of medical titanium materials can change significantly, which affects their mechanical properties and biocompatibility. For example, nanocrystalline and submicron crystal structures can be formed on the surface of medical titanium materials through heat treatment to improve their mechanical properties and wear resistance. In addition, a dense oxide layer can be formed on the surface of medical titanium materials through oxidation treatment to prevent further oxidation and corrosion and improve their biological durability and histocompatibility.

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